Special Issue "Oxidative Stress in Neurodegeneration and Neuroinflammation"
Oxidative stress, neurodegeneration and neuroinflammation are interrelated factors in the aetiology of several brain and retinal degenerative disorders, such as Alzheimer’s and Parkinson´s disease, retinitis pigmentosa, age-related macular degeneration and glaucoma. Oxidative stress results from the imbalance between the production and consumption of reactive oxygen species (ROS). This shift in redox homeostasis can initiate the synthesis and release of pro-inflammatory mediators and the infiltration of immune cells that can further potentiate oxidative stress. These cyclical processes, when uncontrolled, contribute to neuronal cell loss and severe tissue damage.
We invite you to submit your latest research findings or a review article to this Special Issue, “Oxidative Stress in Neurodegeneration and Neuroinflammation”. We aim to gather the latest research about the role of oxidative stress in neurodegeneration and neuroinflammation. We welcome submissions concerning all research models (e.g., in vitro, iPSC-derived cells, organoids, animal models), focusing on all the different nervous system tissues and cell types (e.g., retina, brain, spinal cord, neurons, microglia, astrocytes) and using all types of molecular and cellular approaches that contribute to unraveling and clarifying the pathophysiology and the molecular mechanisms related to neurodegenerative disorders.
https://www.mdpi.com/journal/antioxidants/special_issues/Oxidative_Stress_Neurodegeneration